Involved in transport of phospholipids. Contributes to transmembrane flipping of lipids. Requires an interaction with a protein of the ALIS family for activity. Specific for phosphatidylserine and has no activity with lysolipid, phosphatidylcholine or phosphatidylethanolamine.

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.

1107 amino acids

MKRFVYINDDEASKELCCDNRISNRKYTLWNFLPKNLWEQFSRFMNQYFLLIACLQLWSLITPVNPASTWGPLIFIFAVSASKEAWDDYHRYLSDKKANEKEVWIVKQGIKKHIQAQDIQVGNIVWLRENDEVPCDLVLLGTSDPQGVCYVETAALDGETDLKTRVIPSACVGIDLELLHKMKGVIECPVPDKDIRRFDANMRLFPPFIDNDVCSLTIKNTLLQSCYLRNTEWACGVSVYTGNQTKLGMSRGIAEPKLTAMDAMIDKLTGAIFVFQIVVVLVLGIAGNVWKDTEARKQWYVQYPEEAPWYELLVIPLRFELLCSIMIPISIKVSLDLVKGLYAKFIEWDVEMIDQETGTASYAANTAISEDLGQVEYILTDKTGTLTDNKMIFRRCCIGGIFYGNENGDALKDAQLLNAITSGSTDVIRFLTVMAICNTVLPVQSKAGDIVYKAQSQDEDALVIAASKLHMVFVGKNANLLEIRFNGSVIRYEVLEILEFTSDRKRMSVVVKDCQNGKIILLSKGADEAILPYARAGQQTRTIGDAVEHYSQLGLRTLCLAWRELEENEYLEWSVKFKEASSLLVDREWRIAEVCQRLEHDLYILGVTAIEDRLQDGVPETIETLRKAGINFWMLTGDKQNTAIQIALSCNFISPEPKGQLLMIDGKTEEDVSRSLERVLLTMRITASEPKDVAFVIDGWALEIALKHHRKDFVELAILSRTAICCRVTPSQKAQLVEILKSCDYRTLAIGDGGNDVRMIQQADIGVGISGREGLQAARAADYSIGRFRFLKRLILVHGRYSYNRTAFLSQYSFYKSLLICFIQIFFSFISGVSGTSLFNSVSLMAYNVFYTSVPVLVSVIDKDLSEASVMQHPQILFYCQAGRLLNPSTFAGWFGRSLFHAIIVFVITIHAYAYEKSEMEELGMVALSGCIWLQAFVVAQETNSFTVLQHLSIWGNLVGFYAINFLFSAIPSSGMYTIMFRLCSQPSYWITMFLIVGAGMGPIFALKYFRYTYRPSKINILQQAERMGGPILTLGNIETQPRTIEKDLSPISITQPKNRSPVYEPLLSDSPNATRRSFGPGTPFEFFQSQSRLSSSSGYTRNCKDN

124.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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