Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity).

Belongs to the PA-phosphatase related phosphoesterase family.

293 amino acids

MPSPRRTIEGRPLGSSGGSSVPGSPAHGGGGGGSGRFEFQSLLSCRSGADPACARLRASDSPVHRRGSFPLAAACPAQVAPAPPPEDAGMNLNPSFLGIALRSLLAIDLWLSKKLGVCAGESSAWGSVRPLMKLLEISGHGIPWLLGTLYCLLRSDSWAGREVLMNLLFALLLDLLLVAVIKGLVRRRRPAHNQMDMFFTLSVDKYSFPSGHATRAALVSRFILNHLVLAIPLRVLVVLWAFVLGLSRVMLGRHNVTDVAFGFFLGYMQYSIVDYCWLSPLNVPVLFVLWNQQ

31.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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