Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.

Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.

1010 amino acids

MSQAFNLVLFTEIKQAQNVKTGNDKEPNSKLRAIVRISERSSKKTPRATPRDDFVYTWNSTISLKLRSQLKLPLIQISVWDKQAHRSVYVGEVRFFLIGLLKSLAYNEHTSSWESTPQWYQLYSSEDKKSFSSGTILVQFRVQQHLSKKNLFFNAKSDVTLSDQTGSSDLLNQYIQAIETSTPRSLQKKAFDLSNPNEQRFYPDIETNALASSILDCEIDSMLEDFTYRKPNITESSLHDDTLTDTDFESIHSDPTIPSSALVPKRILFIEILSVTDLPPYKSFTRATFDMDPFVVISFGKRTYRTSWRKHTLTPVFNERLAFEVCDYEKNYDLQFSVLDKDKFSFHDQVATGFVSVSELLEEKTTDKPCTDFKPTSSNLILLDKPMNANESADNLLDTKKKKYKRNVNTDATLQGGLLRKYELVMSLDGKKNWSRKTKDEYIPILKFNTRFERYEILRRQLWMHLLQGNDTQMKGTLDLIELNYFVDCLGSNLSDKTLASFFEYYDKNPWVGETLTIEQVIDSLERLVFKRQCANTHENYIINIDTCPLCGQGRLSLRQDLDILKHLSICASRDWSTVNKVLKPSFVSSKAATRRWYSRLLIKLTFGQYTLGGNSANILIQDRDTGYILEEKMNIHVRLGIKLLYKSFDKANSRKIKTLLRKLSIRQGIKFDSPSSVSQIPSFIKFHKLDVDDCLLQLDEYKTFNEFFYRKLKPGSRPQEDENNSNIATSPADCRCTVFESITFAKTFWIKGRNFTTKKLFGSFYSREMADLYDECSIGIFRLAPQDYHRFHSPVTGTVGKVQSISGEYFTVNPMAIRSDLDVFGENVRCLLPIQTKEFGRVLVVPVGAMMVGSIILSVKENQEVKKGDELGYFKFGGSTLLVLFPNKRFKFDSDLLANSNNKIETLIKVGMSIGHTPEEPQFERHYRSFEEEPVDQQLRIIRCITGGSTFEESKQATQRRNELLGNEGSPQEKDLQVENLSWEAKNMNLEELEENESLLLYDLVNDGT

116.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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