Plays a role in the phosphorylation of phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate (PIP). Involved in the regulation of vesicular membrane trafficking (By similarity).

Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.

492 amino acids

MEPKQTADARDSPPLLVFLEPAAEEVTAHTAPLSPNPQSARAAPGSAVRFFSDSAREEEAGEDEPLLKKSGPVSPRAARKGRTRLSSSSDRENMSGGHVGNGEFNVILDDLEFADIIHRAEQAIESGVFPERISQGSSGSYFVKDPKGKIIGVFKPKSEEPYGHLNPKWTKYFHKICCPCCFGRGCLVPNQGYLSEAGAYLVDEKLGLGVVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVDGYKEADYWLRKFETDPLPENTRKQLQCQFEKLVILDYVIRNTDRGNDNWLIRYDSQDDDELMEKGDDFPLKDWKEIKEPVIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSQETRDLILPRISDMNFVQDLCEDLYELFKTDKGFDKATFEKQMSVMRGQILNLTQALKDGKTPIQLVQMPRVVVERSCSGSQGRIVQMSNAFTQTFHCRKPFFSSW

55.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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