The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).

Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.

533 amino acids

MAVALDPLTDRFSQFSRSSQRCRLQSLTNLDFNFLGFNTKQTNLSASSHSLNNRSVSTPCFSISGSNLDGSATPHIEILGGQRVPTVRSLVAEVTIAIVSGAQPLLLPSGLGGAYLLQTEKGNNIAVAKPVDEEPLAFNNPKGSGGLTLGQPGMKRSIRVGESGIRELAAYLLDHQGFSSVPPTALVRISHVPFHDRGSDHAAYKVASLQRFVGHDFDAGELGPGSFTVVSVHRIGILDVRVLNLDRHAGNMLVKKIHDQDETTCSNGVGAAELVPIDHGLCLPECLDDPYFEWLNWPQASVPFTDIELQYISNLDPFKDAELLRTELDSIQESSLRVLIVCTIFLKEAAAAGLSLAEIGEKMTRDICRGEESSSVLEILCNKAKASAVSGSDDDDDYSSEWNEVEAELECGIFQFDDEVECKELPDMLQVPIFTRVPSIAANLSALMRCPPNQWISTYDTNIEEERRDRSIVRSKSHPICVNYDEKEGVYFGDMSGDEWEMFLHSFQMLLPEALEGSTSKGPKPRFGSSCKF

58.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make PI4KG8 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here