Description
Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores (By similarity).
Family
Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.
Species
Mycobacterium sp. (strain MCS)
Sequence
MEAVVTSSQTVRAEVAELLGIEESALDPDADLIASGLDSIRMMSLSGRWRKQGIDVRFAAMAANPTVAAWTRLVGERTAESPGAATQSGDTAASAGDPDAPFPLAPIQHALWVGRNELTELGGVAAHLYVEFDGAGVDPERLRTAAAALAARHPMLRVDILGDGMQRISDRDLPVKVTDLRHLDVADAEQQLEVIRHAKSHQLLEGEVLELALTLLPDGRTRLHVDLDMQAADAVSYRNFMADLAALYRGAQLPELQYTYRQYRSAFTATPAPTVDEDRRWWTERIPDLPEPPALPLVPRAEQRDPRRGTRRWHFLDTDIRDRLFAAARARGITPAMAFAASYAGTLARWSTSRHFLLNLPMFGREPFHPDVDKLVGDFTSSLMLDVDFTEAHTPAQRARVMQEALHTSAEHATYSGLSVLRDLSRHHGSPSLAPFVFTSALGLGDLFAGDVTDQFGTPVWHISQGPQVLLDAQVTPFDGGLLVNWDVREDAFRPGVIDAMFAYQLAELERLAADDAAWDAADPPAVPPAQRAVRDAVNDTGARRSDDALHDGFFRTAAHTPDATAVIGSTGTLTYAELRERVLAVTGALQVAGIKPGDTVAVMGPKCADQVTALLAIHAAGAVYVPIGADQPADRADSILQTAGVRMALACGDEPPTFLPALTIAEAVRVGSRVHGVTPATVEPDRVAYVLFTSGSTGAPKGVEVTHAAAMNTLEFINDHFGIGPSDRSLALSTLEGDLSVLDVFGMLRAGGSLVVVDEAQRRDPDSWARLIAEHSVTVLHWMPGWLEMLLEVGGALPSVRVVPTGGDWVRTEMVRELRRAAPGVRFAGLGGATETAIHNTICEPGELPREWSAVPFGRPLPNNACRVVAADGADCPDWVPGELWVGGRGIARGYRGRPDLTAERFVVHDGRTWYRTGDLVRYLPDGQIDFVGRADHRVKISGYRIELGEVEAALRRIAGVEAAVAAVLTAPGDGRGEQLAAIVRASSPAVTVDELTRRMAELVPPHMVPSHIALVEAVPFTVGGKIDRRAVTAELTRSMAERANAQAPTYRVPSTALERALADIVSTVLDRDSVGADDDFFELGGDSVLATQAVARIREWLDSPGVMVTDIFAARRVGALARRLVDHESGSDRLEGVAELYLEVADMNSADVASALHSTSAQASR
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service