Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).

Belongs to the SIL1 family.

427 amino acids

MKLSKGVLSSILLTLLIKPIESSIVNTDGELICAPNNPTDCYPKIFEPTTEWQTIREGQDIPAGLHVRLNMENLAREAKILDPSEETEGSSELMVNAEQNNDNGDNSHQMTNEDQANEIQQKIKEFKQTQGKSKVSTVDLNDFQSSVDEVQHYREGGDANRLSTALDTLIDLSHDIEFGVKLTQDSSVFRSLVDVSKSVQDEDLQEKVYRIMGSSLRNNPDAVNHVLKNQDATFVECLFDKLDTDASDVIKKRILGIIHALTQNSHFNAKYFNSNNANSAVDSLISVFPSLESQSQTRLMNILEDLKLLGGANSNEKRAIEESADPKSQYSHFLQHSLADSGVASEDQFKLYFNKLSEVHSQDKSLKPSKAFMEWLSKEAELRSKGNKERDSSYTEEDRQFDQDLLRARHVVFGNPMGLRKALADEL

47.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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