Description
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). Involved in the regulation of early eye development.
Family
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Sequence
MSNPTGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRSYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEVNGSTQHFSSTALPTPTFFTTVRQLEAHNLELAAISTVPERQTLVGLAQPTPKYPHEVNGAPLYLYEFATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDASTLLAVSGMNNENTESPKLNKIISEIQALQDVVSRFRQLRLDATEFACLKCIVTFKAGVSTHSGSELRNFRNAAAISALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSINPSTIEEVFFKKTIGNVPITRVLSDMYKSSDI
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service