Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

803 amino acids

MTGLEEDQEFDFDFLFEFNQSDEGAVAAPAEHYGYAAPGLGAGLPLSAAHPSLPAPCHDLQSSAAGVSAVGYGGTVDSGPSGYFLSSGGIRPNGAPALESPRIEITSYLGLHHNSSQFLHEVDVEDVLPKRSPSTATLNLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESSFSYPYASPQTSPWQSPCVSPKTTDPEEGFARGLGACGLLGSPRHSPSTSPRTSVTEESWLGARTSRPSSPCNKRKYGLNGRQLSCSPHPSPTPSPQGSPRVSVTDDTWLGNTTQYTSSAIVAAINALSTDSSLDLGDGVPVKARKTTLDHSPAVALKVEPAGEDLGTTPPTPDFQPEEFAAFQHIRKGAFCDQYLSVPQHPYPWARPRSPASYTSPSLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPSVQLHGYVESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAVVCSTKVLEIPLLPENNMRATIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPNGRTLSLQVASNPIECSQRSAQELPLVEKQSAASGPVLGGKRMVLSGHNFLQDSKVIFVEKAPDGHHIWEMEAKTEGDLCKPNSLVVEIPPFRNQRITSPVQVNFYVCNGKRKRSQYQHFTYLPANVPIIKTEPSDDYEPALTCGPMSQGLSPLPKPCYGQPLALPPDPGACLMPGFPPRPQGSASPELHDLSCAPYGSATAGPGHSPLGLPRPVGGVLASQEAPRPSGVPPGPPQPPPPTLLQPQVSPTSSG

85.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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