Description
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.
Family
Belongs to the prokaryotic Ku family.
Species
Geobacter uraniireducens (strain Rf4)
Sequence
MAGGTIWKGYIHFADTDVAVKLHAAVKAERIQFHLLHKRDHVKLHQQMICAYEKIPVPTEAQTKGFEVEEGKYIIVDPDELEQTAPESSRMIEVHEFVKTGQIDPIFLDRVYYLEPDLHSEGYSELVGALQEMGAEGICTWTMRNRSYLGALQASGKILRLNTLRYADEVISVKSLELQESPVSEKELKIGSDLINQLTTPFQPQKFENEHEKKLQKLIEKKARGEKIALLRPRLLKPTASDKLLQALEESLKKVA
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service