DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).

Belongs to the NHP6 family.

99 amino acids

MAKADTKTKSSTSTQKRTTKAKKDPDAPKRPLSAYMFFSQDQRERVKNANPEAGFGEVGRLLGAKWKEMSEAEKKPYNDMANRDKARAEAEKAAYNKRR

11.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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