Description
Catalyzes the reduction of nicotine blue to its hydroquinone form. Nicotine blue is the name given to the compound formed by the autocatalytic condensation of two molecules of 2,3,6-trihydroxypyridine, an intermediate in the nicotine degradation pathway. May play a role in preventing the intracellular formation of nicotine blue semiquinone radicals, which by redox cycling would lead to the formation of toxic reactive oxygen species. Besides nicotine blue, several other quinones are reduced by nboR.
Species
Paenarthrobacter nicotinovorans
Sequence
MGDTDLPCVTGVLLAAGAGKRLGRGPKALLPYRGRTLVEDAAETMLVGGCHEVVIVLGANAQAVCARANLEPYRIVVNHDWSSGMGSSYLAGDAAAHTKNHILVALVDQPGLSVTTVGRLLVSHRPGRISSAAYSSLDSPRVLRRGHPMVIDAGLRPAVASTVSGDAGARVFLRQKPWLVDLIDCSDESTGEDVDTVEQMYRLL
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service