Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity).

Belongs to the 'GDXG' lipolytic enzyme family.

408 amino acids

MRSSCVLLTALLALAAYYIYIPLPSSVSDPWKLMLLDATFRSAQQVSNLIHFLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSIVYIHGGGWALASAKIRYYDELCTTMAEELNAVIVSIEYRLVPKVYFPEQIHDVVHATKYFLQPEVLHKYSVDPGRVGISGDSAGGNLAAALGQQFNQDTNLKNKLKVQALIYPVLQALDFNTPSYQQNMNTPILPRYVMVKYWVDYFNGNYDFVQAMIVNNHTSLDVDEASALRARLNWTSLLPTSITKNYKPVMQTTGNSRIVQEIPQLLDARSAPLIADQEVLQHLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL

46 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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