Acts as a transcriptional activator. Plays a role as a differentiation factor during neurogenesis. Required for the conversion of cells within the neural plate and ventral ectoderm into differentiated neurons. Promotes the differentiation of late-born retinal amacrine cells, but not early-born retinal ganglion cells. Its function is inhibited at early stages of retinal cells differentiation.

352 amino acids

MTKSYGENGLILAETPGCRGWVDECLSSQDENDLEKKEGELMKEDDEDSLNHHNGEENEEEDEGDEEEEDDEDDDEDDDQKPKRRGPKKKKMTKARVERFKVRRMKANARERNRMHGLNDALDSLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQSQDIQSHMQTASSSFPLQGYPYQSPGLPSPPYGTMDSSHVFHVKPHSYGAALEPFFDSSTVTECTSPSFDGPLSPPLSVNGNFTFKHEHSEYDKNYTFTMHYPAATISQGHGPLFSTGGPRCEIPIDTIMSYDGHSHHERVMSAQLNAIFHD

39.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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