Protein expression services for mupP | N-acetylmuramic acid 6-phosphate phosphatase
Description
Specifically catalyzes the dephosphorylation of N-acetylmuramate 6-phosphate (MurNAc-6P) to MurNac (By similarity). Is involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc (PubMed:28351916). Plays a role in intrinsic resistance to fosfomycin, which targets the de novo synthesis of UDP-MurNAc (PubMed:28351916).
Family
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. Phosphatase MupP subfamily.
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
226 amino acids
Sequence
MKRMRLKAVLFDMDGTLLDTAPDFIAITQAMRAAHGLPPVDEQRVRDVVSGGARAMVAAAFGLSLDSPEVEPLRQEFLDRYQEHCAVLSRPYDGIPELLAAIEKAGLIWGVVTNKPVRFAEPIMQRLGYAERSRVLVCPDHVTRSKPDPEPLLLACSQLGIDPSRVLFIGDDLRDIESGRDAGTKTAAVRYGYIHPEDNPAHWGADVIVDHPRELIDVLDRALCDC
Mass
25 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make mupP using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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