Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1.

In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

597 amino acids

MPSARLLVLFGSQTGTAQDVSERLGREARRRQLSCRVEELDSYPVVNLINEPLVIFVCATTGQGDPPDNMKSFWRFIFRRSLPSTALRQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAIDPWLQDLWEKVLGPHPVPLNLDLSPPGVLWPSKFTLQFLKDTPSSGPEELCAAGTDPQGPPSELQPFLAPMVSNQRVTGPSHFQDVRLIEFDISGSGISFAAGDLVLIQPENTASHVQQFCQALGLDPEQHFTLQPREPGVTCPTRLPQPCSVRRLVSQYLDIASVPRRSFFELLACLSPHELEREKLWEFGSARGQEELCEYCTRPRRTALEVLCDFPHTAAAVPPDYLLDLLPLIRPRAFSIASSLRAHPSRLQILVAVVQYQTRLREPRRGLCSSWLASLDPAQGPVRVPLWVRSGGLTFPKTPDVPVIMVGPGTGVAPFRAAIQERVAQGETGNVLFFGCRRRDQDFYWEAEWEQLQARGCLTLVTAFSREQEQKVYVQHRLRALGPLVWELLDGRGAHFYLAGNAKYMPADVCDTLLSIFREEGGLSDPDAAAYLAQLQRTLRFQTETWA

66.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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