Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Belongs to the complex I 51 kDa subunit family.

493 amino acids

MLSRTAAPTKASARTLSRAAAEQCRTFATVQDGSANPVRHYGGLKDQDRIFQNLYGRYPPDLKHAKKMGDWHKTKEILLKGHDWIIGEVKASGLRGRGGAGFPSGLKWSFMNFKDWDKDDKPRYLVVNADEGEPGTCKDREIMRKDPHKLVEGCLVAGRAMNATAAYIYIRGEFIQEAAILQNAINEAYADGLIGKNACGSGYDFDVYLHRGAGAYVCGEETSLIESLEGKPGKPRLKPPFPAAVGLFGCPSTVANVETVAVAPTICRRGGNWFAGFGRERNQGTKLFCISGHVNNPCTVEEEMSIPMRELIDKHCGGVRGGWDNLLAVIPGGSSTPILPKHICDTQLMDFDALKDSQSGLGTAALIVMDKSTDVVRAISRLSHFYRHESCGQCTPCREGSKWTEQIMKRFEKGQGREREIDMLQELTKQVEGHTICALGEAFAWPIQGLIRHFRPELEARIRKFAQENGGEALAGGWQRNARQQGKLVSPGM

54.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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