Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1568 amino acids

MSFEVGTRCWYPHKELGWIGAEVIKNEVKDGKYHLELSLEDDEVVSVDTEDLNDDKNQSLPLLRNPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSTTIQHQVEMSETEQRILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKETSIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTKIAGIDDAEEYQTTVDALTLVGITTATQHQIFKILAALLHIGNIEIKKTRNDASLSADEPSLKLACELLGIDSYNFAKWITKKQIVTRSEKIVSNLNFNQAMVAKDSVAKFIYSALFDWLVENINTVLCNPDVDDQINSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVAEEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQKLYQTLDKSPTNEVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLINILEGLENAAKKLEETKKAELEQNNPGNKKPGPARTVNRKPTLGSMFKQSLIELMSTINSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEEWDLIFQKKETTEDDIISVVKMILDATVKDKTKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVTIQKKIRAKYYRNQYLKISQAIKIWQSNTRGFIIRHRVYHEMKVHSATLIQATYRGYAIRKNVFNVLITIINLQTRIREELKRKQLKREHEYNAAVTIQSKVRTFEPRSTFLNTKRDTVVVQSLIRRRAAQGRLRQLKSDAKSVHHLKEVSYKLENKVIELTQNLASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLVNIDNQKNKDMELQKTIEDNLQSTEQNLKNAQLELEEMVKQHNELKEESRKQLDELDETKKALVEHQTLNGDLQNEVKSLKEEISRLQTAMSLGTVTTSVLPQTPLKDVMGGSTANYNSLMLDNAELSPGKSRTTPMSGNHIDSLNIDQDNGANATQINEELYRLLEDTEILNQEITEGLLKGFEVPDAGVAIQLSKRDVVYPARILIIVLSEMWRFGLTKQSESFLAQVLTTIQKVVTQLKGNDLIPSGVFWLANVRELYSFVVFALNSILTEETFKNGMTDEEYKEYVSLVTELKDDFEALSYNIYNIWLKKLQKQLQKKAINAVVISESLPGFSAGETSGFLNKIFANTEEYTMDDILTFFNSIYWCMKSFHIETEVFHAVVTTLLNYVDAICFNELIMKRNFLSWKRGLQLNYNVTRLEEWCKTHGLTGGTECLQHLIQTAKLLQVRKYTIEDIDILRGICYSLTPAQLQKLISQYQVADYESPIPQEILRYVADIVKKEAALSNDSKGHEHSSGIFITPETGPFTDPFSLIKTRKFDQVEAYIPAWLSLPATKRIVDLVAQQVVQDGH

179.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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