Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).

Belongs to the TIM50 family.

471 amino acids

MLRNTRLLTRTISSSLRFAATKNTRLPTQHKFYSKKTDKKAEEPQSILTDDLLAKAGFEDPNEPKEKSEQQESENGEPSEEEKSNGQEQRSRRKRRAQTSKDIQRERYANMFYLATLVGGIAGVGYMCRDWDSEDEQTKLEGKDIDNGFAPNLMYGRLNKRLGSLFTFFSEPVFENLLPPPAPEAYRRPLTLVVTLDDLLIHSDWDTKHGWRTGKRPGLDYFLGYLSQYYEIVIFGSNYQMYSENTVGKLDPFHAYVSYALFREACRYKDGKLVKDLSLLNRDLGKTVLIDVEEDSWSMQPDNAIPMKPWDGSYDDTLVKLIPFLEYLATQPVKDVRPILNSFKDKSNIVQEFAEREAKLREQWKKDNKHLFDSANRPNAGNFLASLMGVPTSSVNKEPKMPLDIIREHGQLQYEHFQKYLKENAPKFLEEEQKLKDEFGKVSLNKLITEGAPSADDIAKVQAERAAAQQQ

54.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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