Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) (PubMed:11769251,PubMed:8899999). Cleaves both linear MC and the tetrapeptide degradation product of MC (PubMed:11769251). Cleaves the Adda-Glu peptide bond of linear MC heptapeptides (PubMed:22591122).

Belongs to the peptidase M81 family.

single

507 amino acids

MLDRRTLMGGILSMAGSKATGAALPGRRLRVFVATLGTETNSFSPLPTGLDAFRATMLWRPGEHPDFATEATGPLWAARERAREGRYEVIEGTCAFAMPGGPVSAQAYQLLRDEILDQLRRAMPVDIVAFGLHGAMLAFGEDECEADLLERARAIVGPDVALGAELDLHAHLSQRLVRAADVLVAFKYYPHIDYVERARDLLDLLERIRAGEIMPTSSLFNCQMVAGLATQSSPMKELVADLFEFERRGEVLSGSLIQGFRAGDVARMGSKVLIYTNNDQPAAASIAQDFGRRYQAMASIMKGNGPERSFAADIELAKAATAYPVILVDSSDNPGGGASGDNMALARAMLDNDLVPSCIGPIWDPLAVQLGFEAGLGADFSLRVGGKVGEASGLPLDVRGKITGLAENVTQNLQGSRPPLGRVVCISTAGLDIIVSEIRDQCYGPDMFRALGVEPANKRYVAVKSSEQWRIGFGDMGRSVIYVASSQQSSIRHYHKRSRPMWPFEPV

54.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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