Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.

Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

334 amino acids

MRVLASAPAKIILFGEHSVVYGKPAIAAAINLRTYVWAEFNERGAIKIEAKDIRVPGLTVSFSEDEIYFESDYGKAAEVLSYVRQAIELVREEADKNGRGITVSITSQIPVGAGLGSSAAVAVATIGAVSRLLGLELTNEEIGKLGHRVELLVQGASSGIDPTVSAIGGFIHYEKGKFEPLPFMELPIVVGYTGSSGSTKELVAMVRRTREEMPEIIEPILLSMGKVVEKAKEILLSDLEEKIRFERLGKLMNINHGLLDALGVSTKKLSELVYAARTAGALGAKITGAGGGGCMYALAPEKQSEVATAITIAGGTPMITEISKEGLRIEEVIP

35.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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