Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 22 family.

121 amino acids

MSNQVLLDKLDRTTESLSQALAQLVKLSSIDRASADSDGDNDGTTDSITSVATNGVMMVHAHTTQLIRGVQDLLVITRAIRETWVLGQIPKKNGDEDAIDYEKCERLLEKAMDDFFGPVAL

13.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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