Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc) (By similarity).

992 amino acids

MVMRTRPLAAMAVRSCFSALTGTVYLLLVLCEVSWAQIFSFPFQRPETCDLNQYFDISALSCAPCGANQRRDALGTSCICLPGYHMISNNGGPSIICKKCPENMKGVTKDGWDCISCPNGLTAEGKCHCPSGHILVERNVSGSLLSQATCELCDGNENSFTKPNALGTRCVRCEPTFVNTSRSCSCSEPHISTGGLCFSNTGNFPQRLISTERYGELGMSSNSEWFTKYLQATAAACWTHSNLTSCQALGNMCVMNMNSYDSTTFDACRLFHYVFEGAAGLTGVHSVPFWRQNLPWLFYGDQPGLASQVLSTTPLPTNFSFKGQNQLKFVAASYDIRGNFIRWQTVKGGVLQLCPDTERRLDAAYSFGTTYQQNCEISLSKLLADFPSPVFYDIYLEYTDEVQHHYLWAIPVLNLNLQHNKLFVNQDSSSSKWLLTRRIFLVDAVSGRENDLGNQPRVIRVATQISLSIRLVPNTKNGNIYTPLLTIAYSDIDIKNAYSQSVKISFSVKYEMNQGDAFVQTDIALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQTVMKFLLYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHKLISQITIDIFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGFKNLALMDPSSSLSRSLSDYAAPYSRILRYAVATTIWLVIGIVQVVFFAAFYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYYIHGRSVHGHADTNMEDMNMNLRREAENLCSQRGLVPNTDGQTFQIAVSSQMRQHYDRIHETLTRRNGPARLLSSSGSTLEQSIKAYHAMNKFLGSFIDHVHKEMDYFIKDKLLLEKILGMEFMEPLEKSIFYNDESHSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFVLASFLTYLQQEIFRFIRNTVGQKNLATKTLVDERFLI

111.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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