Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).

Belongs to the ADPRibase-Mn family.

340 amino acids

MADKLVPSSPADASEPLFSFGVIADIQYADLEDGYNYQRSRRRYYRHSLIHLQGAIEDWNKESSMPCCVLQLGDIIDGYNAQYKVSEKSLELVMNTFQMLKVPVHHTWGNHEFYNFSRDYLASSKLNSKFLEDQIAQHPETTPSENYYAYHFVPFPKFRFILLDSYDLSVLGIDPSSPKYEQCMKMLREHNPNVELNSPQGLSEPQYVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPIYPEASDSVCLAWNYVDALSIIWSHKCVVCFLAGHTHDGGYSEDPFGVHHVNLEGVIETAPDSQAFGTVHVFPDKMLLKGRGRVPDRIMNYKREEAL

38.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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