Description
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
Family
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
Species
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Sequence
MQKPLIELKGVSRVFNLGGLAVEVLKGIDLQIYPGEFVAIMGASGSGKSTLMNILGCLDRPSQGEYLFRGESVSLLHRDDLAQLRREEFGFIFQSYHLIHALDARENVEVPAIYAGAGIVEREKRAEELLGSLGLGERLHHRPSQLSGGQQQRVSIARALMNGGRVILADEPTGALDSRSGEEVMQLLMELSRQGHTIILITHDSHVASHANRVIEMKDGQITHRQEPVIRESNQVRSPFGVRHSSILLELFEAMKMAFRSLKMNLFRTVLTLLGIVIGVASVIVMLAIGDGAKNAVLERISAMGTNILVIRPGMPNSRGFSNIATLIPEDMEAIMELDNIIAAMPENKKSVTTRYGNNDQSTSLNATSSHFTKVRNWPLGKGVFFTEEDEKSYAKVVVLGKTVEKALFGEEDALGRFILVDNIMFQIIGVMSNRGASASGEDEDDVILVPYTTGSLHLIGQKFLRNITVAVDDLSRMGETEREIHSLLLARHGGIEDFRIRNMASLIEDVTQTQNTLTILLGSIAAISLLVGGIGVMNIMLVSVTERTKEIGIRIATGARMRHILQQFLIEAVVVSALGGLIGVVIGLGVSALIEGLGTPVYYSLMPIVWAFGCAFVTGLLFGYLPARKAARLDPVVALASE
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service