Description
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
Family
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
Species
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Sequence
MSGAGLELDGVWRRFPSGEDEVAVLKNVTLSIAPGEMVAIVGASGSGKSTLMNILGCLDQPSVGRYRVAGQDAGCLDGDQLAALRRGHFGFIFQRYHLLPHLSALDNVAMPAVYAGMALHQRRERARALLARLGLAGKEHHRPGQLSGGQQQRVSIARALMNGGRIILADEPTGALDSHSGEEVMRILKELNAAGHTVIIVTHDPAIAAQTERVIEIRDGEILRDSGAPAREAASQATEAQPDGGPLLRERLAEAFKMAMLAMSANRLRTALTMLGIVIGIASVVSVIAIGEGSRDYVLKGIREMGTQTITVFRGKDWGDDKADGVRTFLPGDVAALEGEGYVDSVTPETAQAQRIRYRNVDVNASVIGVGRDFFRVQGMKLAEGQSFSRDDIHFQRQVVVLDKNSRRKLFGDGEAVGRVILVGMVPATVIGVVAQRDRGFGGNSLQMWMPYSTAASRLFGQQHFDRFVIRVKDGQPTKLAEKAIGALLTQRHGGKDFFTYNMDEILKTVESSSRALSLLLALVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARQGDVLQQFLTEAVLVCLVGGAIGVALSYGVSFVFSLFVTEWKMSLSPPVIALAVACSSLIGVLFGFLPARNAAKLNPIDALARE
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service