Description
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
Family
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
Species
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Sequence
MADTPPPLIELIDLERVFDSSEVPVRALDRVSLTIHEGEFVAIIGQSGSGKSTLMSILGCLDRPTGGLYRLGGIDVASLDPVALAGLRRDTFGFVFQRYNLLAGASAAENVEMPAVYAGQPRHQRLERAHALLDRLGMGARSGHFPNQLSGGQQQRVSIARALMNDPRVILADEPTGALDSASGRDVLALLEALHTEGRTVILITHDRDVAARAERVIALQDGRVVEDSGRPAPVGSDRPLGRPPGGAAYLGMAASFGEALKMAGRSLRANIFRTALTLLGVVIGVAAVVTMMAIGEGSKQDVLTRIQSMGTNLLLVRPGAPGIRPSGTDVSLTPTDAEAVAQLAGMAAVAPERMASGITVRREGIDYRTTINGTWPAYAAAKDWPMAWGSFFDATDLQASAPVAVLGQTVAKNLFPGEEDPVGSYFLVRNVPFLVIGVLEAKGATPFGQDQDDIVLIPLTTAFARVSGGRYLSSLTARVEDATTIDESQAAIESLLQARHGKVDFQVRNTQSLLEMVEKTQNSLTLLLGAVALISLLVGGIGVMNIMLVSVTERTREIGIRLATGARASDILLQFNTEAVAVCGVGGLAGVGLGLGAALAVAEFGLPVRFTPGPPIVAFCCAFLTGLLFGYLPARKAARLDPVVALSAE
Simulated SDS-PAGE
![Western blot of macB recombinant protein](/recombinant/macB-45.png)
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service