Protein expression services for calB | MFS-type transporter calB
Description
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds. Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells. It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828). Required for the secretion of calbistrin A and calbistrin C, as well as of related compounds decumbenone A, B and C (PubMed:30598828).
Family
Belongs to the major facilitator superfamily. TCR/Tet family.
Species
Penicillium decumbens
Length
562 amino acids
Sequence
MDEVTRTAQRSPSITETHAGETKLAGPGEKEGDVESPVDPSADSEQNRQQITGLQLFAILASVTLSAFLMLLDGSIIGVAIPNITSQFHSIDDIGWYTAAYQLASAALQPLSGKIYSSFSTKWTYLFFFGLFELGSLICGVANSSSMLIGGRAVAGLGSSGLLNGGMTIIAGAVPLEKRPVYTGIYLGISQLGIVCGPLIGGALTEYTTWRWCFYINLPVGAVTAILLLFLQVPELTEKPRFTFALVRRVIPELDLIGFTLFAPAAIMVLLALYYGGNDFPWDSSQVIGLFCGAGVTIIVFALWERRVGDRAMIPPSMVSHRIVYTSAINGAALVASILVAAQYLPIYFQGVRGYGPAMSGVNTLPGILSQLLTVILSGVLVQKVGYYLPFAAAGSAISAVGNGIVTLFSPTTPTAKWIGYQIVLGSGRGIGMQMGIIAIQNLLPPEKISVGIAFMIFCQNFAGAIFVVVGEVIFTQQLVKQIQAHAPSVKVDAALAAGASSSSLRALVPPGSPELQGVLLAFSNSVDRVFYLLMSLSLAGFVAAFGMGWVDTRKKNKSETE
Mass
59.5 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
Make calB using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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