May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

466 amino acids

MVQKKTTEMKGFHRSFKGQNPFDAAYEMESRNMASVFNFDCPSRPDVPSSAPIDIPDAKKRTKKKKRCRATDSFTGRFEDMYQLQQEILGEGAYAKVQSCINLITNKEYAVKIIEKRPGHSRSRVFREVEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKMCGGSILNHIHRRRHFNEREASFVVRDIAEALNYLHNKGIAHRDLKPENILCESPHQVSPVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEEASIYDKRCDLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPACQNMLFVSIQEGKYEFPEKDWAHISSGAKDLISKLLLRDAKKRLSAAQVLQHPWVQGNAPDNTLPTPIILQRNSSAKDLTSFAAEAIAMNRQLMEREEEEEGTESSSSCPIVVKATSCSMQLSPPSESKLAKRRHGSKGGISPPSLAPLLIVSD

52.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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