Protein expression services for KDM5B | Lysine-specific demethylase 5B
Description
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor. May repress the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
Family
Belongs to the JARID1 histone demethylase family.
Species
Gallus gallus
Length
1522 amino acids
Sequence
MAEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGCTLKIPHVERKILDLFQLNRLVAEEGGFDVVCKERKWTKIATRMGFAPGKAVGSHIRAHYERILYPYNLFQSGASLLCLQKPDLTSDTKDKEYKPHDIPQRQSVQPSESCPPARRAKRLRAEATNIKTESDSPEVRTHNLRRRMGCAPPKCENEKETYSAVKLAEKREHAGEQERDKAKARSKKPTSAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPQCLAQECNKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKFKVRPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEQLEDVMKKLAPELFESQPDLLHQLVTIMNPNTLMAHGVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCIEHYRLLSRYCVFSHDEMICKMASKADILDVVVASTVQKDMAIMIDDEKMLREKVQKLGVTDSERVAFELFPDDERQCYKCKTTCFMSAVYCPCKPGLLVCLYHVEDLCSCPTYQYKLGYRYTLEELYPMMNALKMRAESYNEWASNVNEALEAKISNKRSLISFKALIEESELKKFPDNDLLRHLRLVTQDADKCASVAQQLLNGKRQTRYRSGGGKCPNQLTVNELRLFVRQLYALPCVLSQTPLLKDLLDRVEAFQQQSQKLLSEEMPSAAELQELLDVSFDFDVDLPQLAELRVRLEQARWLEDVQMASAEQNSLTLDDMRRLIDSGVGLAPYPAVEKAMAKLQELLTVSEHWDDKARNLIKARPRQSLSSLVVAVKEIEEIPAYLPSGAALKDAVQKAQDWLQEVEALQVGGRVPVLDTLVELVTRGRSIPVHLDYLPRLESLVAEVQAWKECAANTFLCENSPYSLLEVLCPRCDIGTLGLKRKQKKLKEPMPSGKKRSTKLESLSDLERALSESKDTASAMATLGEARLKEMEALRSLRAANEGKVLCSEEDAELKVCVCQKEPAAPMIQCELCRGFFHTGCVSVPHALQGPRVWLCPQCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQMLYSGNLKLLQDKVGSGLLYNRWQSTAGPLPETNKVSQTIGAMSFSMPHDWDNRTIYLHSPFSTGQQCIPLHVVSTELDELMMEAQLLQVSLPEIQELYQILFTKQSPSLQAEQKPSVGPSNEKSECCRGKKDGMSYMERKLKRRFERESFCDEKRARVRKMRTPKKKKLKLSHTKDVSSSSRMERERERLLEAQRSSESHLVPSDTSFSEQEDSEDEDAICPAVTCLQPEGEEVDWVQCDGSCNQWFHQVCVGISPEMAEKEDYICASCAGKGSPYRK
Mass
173.5 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
Make KDM5B using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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