Protein expression services for kdm3a-a | Lysine-specific demethylase 3A-A
Description
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
Family
Belongs to the JHDM2 histone demethylase family.
Species
Xenopus laevis
Length
1331 amino acids
Sequence
MVLTQQENLSVLVGQRFTCLLGTDLQLDPDGVSKWPWKSGIVRAASHKDLHCPEIKIFVEFDDEAWEKRTWIELYGATVKMFLVEHNLVLADRVSPSNSVPVQCPAMVYKVLVGKFSLGTATCLQFLGDKDKLFLSKELVKPVRDRETLKQFMQENKTFNKAFQELIRKSVDESRLQQATRNIIGMPINVYSMDPSMQWFSATISNVRTASRALEIKCEQLPSLKIIDPALLHVVLVHNYGDLNDKSRKPRAPKRKSQDTESEDQTELKQTRNEEVPSKDVTQKTSFLTYRRDDGKTLVVVDNPKATNNLFNYINTTTEDQQKVQQQSLSSKQSVPVGFGEALLGCAATTPGILNAATPPQANSPPSFGAATPQGKGTQNLPGDTTLLNGEAKREETNLFLSAAASQGNKRSLGFGMMESPSTFSSLSSMPSWSGQPKSENGPKSENLFAAFTNSSTVFPKGFEFSVKSFPEQKMLSVTDSPKTAPPMTCVQQQEQKVVKKPENNHTSVRAIKPQEPPYPKSPNKNDGVTYPRSILLDPQKLKRLQQSGDCFVQDGSCNDIAPHLHKCRECRLDRFGRSREQRDSAVFCRFFHFRRLHFNKHGMLKEGGFLTPNKYDAEAINLWLPLASNVVDLDLDTAKYILANIGDHFCKLVMSEKEVMSATDPSKQVAWKRAVRGVREMCDACDTTIFNLHWVCPKCGFGVCVDCYRMKKKSLSSGEDGNETFSWLKCVKGQLHEPENLMPTQIVPGKALYDVGDIVHSVRGRWGIKSNCLCSNKHVRPVVKPVVKEEVKPSTPEPEPTKAPLAQPNVCTAPDPIAIPSTPPTPACSSPLSWLTNLSQTTVNKENKDNLFASNLEHKPLPSFASFGKPVSALQTFGSSILTPTTSNNSGFLRNLLNSSTLKQETNEKSTPKILDDIFASLVQSRPLSDFARKPQGLPIQPSLMGFNTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVIVSGIHNNLNSELWRPESFRREFGDQEADLVNCRTNDIITGATVGDFWEGFEDISARLKNDKGEAMVLKLKDWPPGEDFRDTMLSRFEDLMNNIPLPEYTRREGKLNLAARLPAYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDATNVMVYVGIPKGEHDQEQEVIRTIQDGDADELTIKRYIEFKEKPGALWHIFAAKDTEKIRQFLKKVAEEQGHENPPDHDPIHDQSWYLDNTLRKRLLQEHGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSHTHTNHEDKLQVKNVIYHAVKDSIAILKANEASLGKL
Mass
149.6 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make kdm3a-a using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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