Description
Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors (By similarity). Confers resistance to cationic antimicrobial peptides (CAMPs). Promotes the ability of L.pneumophila to replicate and/or survive in macrophages. Important for ability to kill macrophages and to promote the virulence (PubMed:11401964).
Family
Belongs to the lipid A palmitoyltransferase family.
Species
Legionella pneumophila
Sequence
MKRLISCLTIICALNRSAAAETTSSPCSRWISLLKPVCQRIHQTWTEGHDDMYFSGYAWHNRYTYRPEKIKSYNEAAWGGGLGKSLFDEKGNWHGLYAIAFLDSHRHIEPAVGYAYLKTASVNKDIKAGLGYSVLVTSRVDYDNVPFPGALPWVALFYKRTTVAATYIPGSAGAGNVLYILGKISL
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service