Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

Belongs to the L/F-transferase family.

228 amino acids

MIPKLLKHELTFPHPNDATEDGIVAWGGDLNPSRLIRAYQNGIFPWYGKNDPIIWWSPNPRLIMELDDFKLSRSLRKSMKKFEYRFDTNFINVMKNCQNIKRVKQDGTWIQDEIIEAYSVLHDMGIAHSVESYLDGELVGGLYGVAVGGLFCGESMFTLVNDASKSAYAVLINHLKIWGYDFIDAQVPTEHLKNLGAKEVSRDYFLDRLHKVNMNIINHKWELLHVNT

26.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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