Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity).

Belongs to the HDGF family.

579 amino acids

MSRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKMPIFFFGTHETAFLGPKDIFPYSENKDKYGKPNKRKGFNEGLWEIDNNPKVKFSHQPSHPAVNTSIKETIQESSPEAAEGSEEKSGAKRRKPSIPKLPPKGDNNSPAEAEAEEKEMHSTKEDEEPSEKNSKEGVVKTNDASIPKVARRGRKRKAEKQAESEEAAVVATAAVVAAAAAPVTVSPKVSPKRGRPAVSEVKVPKPRGRPKLVKPSCLSESDPVNEEEKAKKKGPDEKPKKQGKKDEEGQKEEEKPKKEYDKKDGKKEAEPKRKNAAKLGSASASDSEDEGGEEEGDKKKKGGRSFQSTHRRNIMRGQHEKEVTERKRKQEEQGESELQNKEEGKKTEVKKMEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVSMQQAQKHTEMILTLKKIRKFKVSQVIMEKSTMLYNKFKTMFLVGEGDSVLSQVLNKSLAEQKQHEEANKTKEQWKKGTNKKNEKEKDQTGSKIVNGGSETQDTNQSQHNGENAEEKDKLEVASKKKTCGEESELEKPAKESAFENK

64.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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