Involved in the acrylate pathway for the conversion of D-lactic acid to propionic acid. Catalyzes the reversible dehydration of Lactoyl-CoA and 2-hydroxybutyroyl-CoA to acryloyl-CoA and crotonyl-CoA, respectively.

Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

single

422 amino acids

MSLTQGMKAKQLLAYFQGKADQDAREAKARGELVCWSASVAPPEFCVTMGIAMIYPETHAAGIGARKGAMDMLEVADRKGYNVDCCSYGRVNMGYMECLKEAAITGVKPEVLVNSPAADVPLPDLVITCNNICNTLLKWYENLAAELDIPCIVIDVPFNHTMPIPEYAKAYIADQFRNAISQLEVICGRPFDWKKFKEVKDQTQRSVYHWNRIAEMAKYKPSPLNGFDLFNYMALIVACRSLDYAEITFKAFADELEENLKAGIYAFKGAEKTRFQWEGIAVWPHLGHTFKSMKNLNSIMTGTAYPALWDLHYDANDESMHSMAEAYTRIYINTCLQNKVEVLLGIMEKGQVDGTVYHLNRSCKLMSFLNVETAEIIKEKNGLPYVSIDGDQTDPRVFSPAQFDTRVQALVEMMEANMAAAE

47.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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