Description
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
Family
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Sequence
MEERKQKVVVVGAGPVGSLAALYAANRGHDVEIYELRGDLRDPSTTPLNFTRSINLALSERGLNAMRHANQPRLIDYVKGVTIPMRGRMIHGKRPDGKLYEEAQDYDIHGRSILAIDRGDLNKRLLDMLEEMPNVTFFFNHKLTGADFKRNKAWFENKDESTSNPRDRAREIEVDFDFMIGADGAHSAVRYHLMKFSRMDYQQEYIDTLWCEFQIAPSSSSAKSKFRISPNHLHIWPGKEFMFIAIPSNDGSFTCTLFAPAAIYEQLEEAGRTGDTSSSIPEFFDMHFPGVTSLIAPADLIAQFQTNPHLPLISIKCKPYHFSSSVVIVGDAAHAMVPFYGQGMNAGLEDVRILFDILDKHDRMTNDDSSLEASQRELALAEYSAVRVADAHAINDLALQNYIEMRSSVLSPVYRWRKALEEWLSVYVPSLGWQTKYSRVSFGNERYSEVVKKSERQGQVLLRSLVGGVGLPMLAGGLFLWFRYKGALGRAAYGVFYNCMGMVCRTIHGRRR
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service