Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (By similarity). The BCR(KBTBD8) complex acts by mediating monoubiquitination of target proteins (By similarity).

Belongs to the KBTBD8 family.

601 amino acids

MAASGDVGKLLQVQNGTPASTSYNGVDALHACNILQQLKALYDEAQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESSQREVRIVGVESESMHLVLDYAYTSRVTLTESNVQALFTAASIFQIPALQDQCAQFMISRLDPQNCIGVFMFADAYGHQELRERSQDYIRKKFLCVMGEQEFLHLTKDQLVSILNSDDLNVEKEEHVYESIVHWLEYDCSRREADLPEVFAKCIRLPLLEEAFLSRIPPAFALALSRDSSDKSRLNGTNGCSQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIAAGKVYKLCKPPNDLREVGILISSENDIFIAGGYRPSNSEVCIDHRAESDFWQYEHAGNRWLPRSPMLRARIGCRLVHCCGKLYALGGRVYEGDGRNALKSVECYDARDNCWTAVSPMPVAMEFHSTIEYKDRIYVLQGEYFFCFDPRKDYWGHLPSMNIPRTQGLAALHKNCIYYIAGICRNHQRTFTVEVYDIEQNTWCRKRDLPFDQATSPYIKVLLLQGRLHLFVRATQVMVEEHVFRTSRKNSLYQYDDEADHWTKVYETPDRLWDLGRHFECVVAKLYPQCLQKVL

68.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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