Description
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).
Family
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
Sequence
MNLTEICDNAKKGREYALLGNYDSSMVYYQGVIQQIHKHCQSLRDPAQKVKWQQVRQELAEEYEQVKSIVSTLESFKVDKAVDFPNPVPEEGPRDPDVWPPPTPAEHRGPVQVKKPVPLSKPQRKESPGMQHRGAVGRGQANIKPDRPNTRDGRGNKAKEEKSKRNAQEGAADVEQKKFDGTGYDSDLVDALERDIVSRNPNIHWDDIADLEDAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICGRRGTSDEHEASRRVKSELLVQMDGVGGAQESEDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKINLREVDVASDVDLTVFAEKIEGYSGADITNVCRDASMMAMRRRIQGLSPEEIRALSKDELQMPVTMEDFELALKKISKSVSAADLEKYESWMSEFGSV
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service