May be involved in different biological processes including transcription and apoptosis by sequestering specific proteins outside of the nucleus (By similarity). Involved in actin stress fibers formation probably through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (By similarity). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457).

1085 amino acids

MTIMAQVLHMDSSFPGKINPPVPPSLHAKDQEAPYSVETPYGYRLDLDFLKYVNDIEKGNTIKKVPVQRRPRYGSLPRGYGYTGSWWTSTESLCSNASMDSRHSSYSYCAPGFHTSQRPNFSTARVEKTLMDARRKLEEEKDGRRFSNLGSMHSSMAGSNTSLSSAHSFNRAQGGGSYTPMSSGLSTPVSPTPAHLQHVREQMAVALRKIRELEEQVKTIPVLQVKISVLQEEKRQLSVQLKSQKFLGHTLGFNRSRPRGELYIDIPEEEAGNGAGAANKATGSLSPTTPGSLQDSGCEIEETVIVAGARPGAKREVRTVGVGPEAEERGYRQVGVGVREQDLGLLPETEALKTKVGLLEVQLRKTMQELQSAQQQVEAAQKERQTVCPQVDHAVRATSLGWQDQQGQAGAGLHTVVSFTKQPHQQRTVGIQVYTLEQPTVVGVGTLLRAQGCTHPAQLEASHRRYGESPAAGDSPHEFPIAISSKQVREVLRSEVSKSVPVTNQATPMETKCNQVTAVCQRLKEGEINQQPAEEAIQVDPANPASPQSNLRSIMKRKADGEPGSPYTKKNLQFLGVNGGYESTSSEESSSESSEDESDASEYHEATEKLPESATPQSLVSSCIPQLASETPATQTAQHSTAQIPTNHTPAAQTTSQSHTTDATTQQHVTQSPAAEADVQHCVSQSSVTTTPPPEGDVQCVFQGCNPPSTATSLEQNSVQLSSATQQSKATDSNVQPDLAQTDVSDFAAQQTTTQTQFTSAKPQQEASQSKTADLTAQKGATHSTDGSAKQDIAISSTTKPAADTATPPTNKQTDSLELSGGLMSALHILQKALSEPNAFSHQDARTAYTSVLQEWLRVSCHKAADTAVVKAHMDAFASISPQLLEFVINMADGNGNTALHYTVSHSNFPVVKLLLDTGLCNADKQNKAGYTAIMLTALAAFSSDSDLQTVLQLLRTGDVNAKASQAGQTALMLAVSHGRGDMVKALLACGAQVNLRDDDGSTALMCACEHGHVDIVRQLLSVPGCDATLTDNDGSTALSIALEASQNDIAVLLYAHLNFAKPPSPVSPKSPILGSSPPSSSELK

116.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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