Description
Monooxygenase that converts the endogenous (and likely the host) jasmonate (JA) to its hydroxylated derivative 12-hydroxyjasmonate (12OH-JA), also known as tuberonic acid, a compound that attenuates or disables jasmonate-based host innate immunity and which is essential for proper initiation and elaboration of the blast disease in rice (PubMed:26258762). ABM, together with a polyketide synthase MGG_04775 and the esterase MGG_04774, share the secondary metabolism gene cluster with ABC transporter ABC3, and therefore may also be involved in the synthesis of other important metabolites such as the ABC3 transporter efflux substrate (ATS) and/or additional polyketides (Probable).
Species
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Sequence
MFAVIFETRPQPSQFDTYLTIAKSLRPELANIDGFIENIRYKSLSRPGWILSLSFWRDEKSLVRWRTTATHHMAQEKGRDGVLEDYHLRVGQVTASVRSNEVKRVETVDAREQDDVTAVGAAKTVQLVRFQMDRGAGIDAAAGKLGLNPEEPRGLLAWDIMEAVLSPGDMILLASWETGSSSVSIPGADSDEVQVLRDYGKYDRREAPQFYPPAS
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service