Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.

Belongs to the iron/ascorbate-dependent oxidoreductase family.

326 amino acids

MNRHADVPVIDISGLSGNDMDVKKDIAARIDRACRGSGFFYAANHGVDLAALQKFTTDWHMAMSAEEKWELAIRAYNPANPRNRNGYYMAVEGKKANESFCYLNPSFDADHATIKAGLPSHEVNIWPDEARHPGMRRFYEAYFSDVFDVAAVILRGFAIALGREESFFERHFSMDDTLSAVSLIRYPFLENYPPLKLGPDGEKLSFEHHQDVSLITVLYQTAIPNLQVETAEGYLDIPVSDEHFLVNCGTYMAHITNGYYPAPVHRVKYINAERLSIPFFANLSHASAIDPFAPPPYAPPGGNPTVSYGDYLQHGLLDLIRANGQT

36.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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