Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor (By similarity).

Belongs to the IRF family.

313 amino acids

MPVSRMRMRPWLEMQINSNQIPGLIWINKDKMIFQIPWKHAAKHGWDMEKDACLFRSWAIHTGRYKVGEKDPDPKTWKANFRCAMNSLPDIEEVKDKSINKGSSAVRVYRMLPPLTKDQKKERKSKSSREARNKSKRKLYEDMRMEESAERLTSTPLPDDHSSYTAHDYTGQEVEVENTSITLDLSSCEVSGSLTDWRMPMEIAMADSTNDIYQLQVSPLGSSSEDEDEMKSNIIKLLEPTQDWHTTSVEGKGFFTNEPGTQTMCSTFGYKEQDGEIDTSSAELEFRMMDQKSSLDFSWLDTVRPMQAISCSL

36 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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