Transcription factor involved in anterior and eye development. Promotes the differentiation of both rod and cone photoreceptors cells in the retina. Together with other retinal homeobox proteins, acts as an effector of a cellular clock which, depending on cell cycle progression, establishes the generation of distinct retinal neuronal cell types. Acts synergistically with nrl to activate the rhodopsin promoter. Promotes the formation of anterior regions and represses the formation of posterior structures during development.

290 amino acids

MMSYIKQPHYAVNGLTLAGTGMDLLHSAVGYPTNPRKQRRERTTFTRAQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSSASATVSIWSPASISPIPDPLSAVTNPCMQRSTGYPMTYSQAPAYTQSYGGSSSYFTGLDCGSYLSPMHPQLSAPGATLSPIATPTMGSHLSQSPASLSAQGYGAASLGFTSVDCLDYKDQTASWKLNFNATDCLDYKDQSSWKFQVL

31.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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