Protein expression services for Setd5 | Histone-lysine N-methyltransferase SETD5
Description
Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 in vitro (PubMed:22939622). The physiological significance of this activity is unclear (Probable) (PubMed:22939622). Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription (PubMed:27864380).
Species
Mus musculus
Length
1441 amino acids
Sequence
MSIAIPLGVTTPDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSNKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNAAELPLPPPPSFPTIGAETRRRKARRKELELEQQNEVPEENPDPQPQEVPEKVTVSNEHEEVDNPEEKPEEEEKEEATDDQENSAHSRRTREDRKVEAIMHAFESLEKRKKRRDQPVEQSSSDIEITTSSSEIVVGEETKTAAPESEVSSPVSNVAIPSTPQSTGVNTRRSSHAGDVAAEKPIPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQAIAQQAELSQAALEEGGSNNSVTPPEAGNTDSSGENRQLTGSDPTVISVTGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFMPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNETSNSSSICKDNADLLSPLKKWKSRYLMEQNITKLLQPLSPVTPPPPSSGSKSPQLTTPGQTHPGEEECRNGYSLMFSPITSLTTASRSNTPLQFELCHRKDLDLTKVGFPDSSTHSCADRPSLLNCNHPDLASHPSVVPTSEAGFPSRSGDGPQTLLRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGFMKDLSRGSMSPGGERTCEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSGGGNDSSQSKSKSSGAGQGSSNSVSDTGAHGVQGSSAGTPSSPHKKFSPSHSSASHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKESDPADGEGPEPLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYPSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSNLPRRSCSSSAASPTPQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPNAGQSAAYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
Mass
157.4 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
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