Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation. Negatively regulates telomere silencing. Telomere silencing is increased due to histone hypoacetylation and/or an increase in the ratio of methylated histones to acetylated histones. Telomeric histone acetylation contributes to normal meiotic progression.

Belongs to the MYST (SAS/MOZ) family.

407 amino acids

MPATILKSTASSKTLLIIKFDTNSSRYPFYKKHLLELNSESTFLGLLTKGQADTSITRLNQDDVRLFEKAKTVADRTKDVAYSFSDPILSTQLRTPPPQPTSIRYLYFGTYRIKPWYTSPYPEEYSCAKNLYICESCLKYMNSDHVLQRHKMKCSWSYPPGDEIYRDKNISIFEVDGQRQPIYCQNLCLLAKMFLHSKMLYYDVEPFLFYVLTEFDGQECKVIGYFSKEKRSASDYNVSCILTLPIYQRRGYGVFLIDFSYLLTQVEGKLGSPEKPLSDLGLVTYRSYWKMRVAKALLEITTPISINAIAKSTSMVCDDVISTLESLSVFKYDPLKKKYVLQLKRDELENVYKAWNIKHPQRVNPKLLRWTPYLGEEQISNLLLKENILIPLPQKRLLDNSHHLDSV

47.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make mst2 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here