Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

Belongs to the histidinol dehydrogenase family.

433 amino acids

MPQFLDSRQPDFETAFTALLGAKREDSPDVDAVVAGIIADVRARGDAAVIELTERFDRVALTPQSLRFSTEEIAQAVDEVPAPERAALELAAARIRAYHERQMPQDADWTDDTGARLGWRWSAVSAAGLYVPGGLASYPSSVLMNAIPAKVAGVGRLAIAVPTPDGQVNPLVLLAAQISGVDEVYRIGGAQAIAALAYGTDTIAPVDKITGPGNAFVAAAKRRVFGKVGIDMIAGPSEILVIADRDNDPDWIALDLLSQAEHDESAQSILITDDAAFGRAVAEAVDKRLETLERRAIAGVSWRDFGAVITVSDLDEAAALSNRIAPEHLELCVSDPEALAARTIHAGAIFLGQYTPEAIGDYVGGPNHVLPTARSARFSSGLSVMDFLKRTTMSRMTPEALRAIGPAAAQLARSESLEAHGLSVQARLDRLNG

45.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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