May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1 (By similarity).

Belongs to the multicopper oxidase family.

1157 amino acids

MKAGHLLWALLLMHSLCSLPTDGAIRNYYLGIQDIQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGGTYKKTVYKEYSDGTYTNEIAKPAWLGFLGPLLKAEMGDVILIHLKNFASRPYTIHPHGVFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPEGHAPTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKDVDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGPFQDSNRMHAINGFVFGNLPELSMCAQKHVAWHLFGMGNEIDVHTAFFHGQTLSIRGHRTDVAHIFPATFVTAEMVPQKSGTWLISCVVNSHLKSGMQAFYKVDSCSMDPPVEQLTGKVRQYFIQAHEIQWDYGPIGHDGRTGKSLREPGSGPDKYFQKSSSRIGGTYWKVRYEAFQDETFQERLHQEEETHLGILGPVIRAEVGDTIQVVFYNRASQPFSIQPHGVFYEKSSEGTVYNDGTSYPKVAKSFEKVTYYWTVPPHAGPTAEDPACLTWMYFSAADPTRDTNSGLVGPLLVCKAGALGEDGKQKGVDKEFFLLFTIFDENESWYNNANQAAGMLDSRLLSEDVEGFEDSNRMHAINGFLFSNLPRLDICKGDTVAWHLLGLGTENDVHGVMFEGNTLQLQGMRKSAAMLFPHTFVTAIMQPDNPGIFEIYCQAGSHREAGMQAIYNVSQCSSHQDSPRQHYQASRVYYIMAEEIEWDYCPDRSWELEWYNTSEKDSYGHVFLSNKDGLLGSKYKKAVFREYTDGTFRIPQPRSGPEEHLGILGPLIRGEVGDILTVVFKNKASRPYSIHAHGVLESSTGWPQAAEPGEVLTYQWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEPNGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQETSHVNLQDATFLESNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFLYQNGHSYRADVVDLFPGTFEVVEMVASNPGAWLMHCHVTDHVHAGMETIFTVLSHEEHFSTMTTITKEIGKAVILQNIGEGNVKMLGMNIPVKNVEILSSALIAICVVLLLIALALGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ

129.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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