Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the specific ventral activation of a series of proteases acting in the perivitelline space between the embryonic membrane and the eggshell. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the egg, whose ventrally localized modification leads to spatially restricted activation of the protease cascade.

Belongs to the sulfotransferase 3 family.

514 amino acids

MSLNAERSYKMKLRDVENAFKYRRIPYPKRSVELIALLAISCTFFLFMHTNKLNSRLKEMEVKLQPSEFSALGLTGNHISGHDAGKHDDINTLHGTYQYLKSTGQKVGYNVHDRRSSEEQLRTPTAHGHHHDHHSHHHHMHQQEKIDGHKHKASHDKQLAVPDNKHKEDEVHYEDDEDEVEENDDDLANDVGTTDSEGFNFKADLLNNTKYAEVDFVFFNRVPKVGSQSLMELMARLGKINGFTHARNKGSAHETIVMNKQRQNDLIADLLTRPKPHIYSQHIAYINFTRFHLPKPIYINLIRDPIDRIISWHYYIRAPWYYRDMQAKLGENAIPMPSEEFMNLDLDTCVRNHDPHCTFTQMQIKNPVGDHRRQTLFFCGMNQKLCMPFNSEAAMQKAKRTVETEYAVVGTWEDTNITLSVLEAYIPRYFRNAKVAYYLGKDRLSRVNRNNVTRIVSDETRLILRKNLTNEIEFYEFCKQRLYLQYAALSHGKRFGEDDYLLVPEQQNEYNEDY

60.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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