Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

590 amino acids

MASEIHMTGPMCLIENTNGRLMVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHVLVLLDTEGLGDVEKGDNQNDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPITADEYLTYSLKLKKGTSEKDKTFNLPRLCIRKFFPKKKCFVFDRPVHRKKLAQLEKLHDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAVAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQDIFSPLEEEVKMGIYSKPGGYRLFIQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASTKMLQEIQRKNEQMMEQKERSYQEHLKQLTEKMERDRAQLLKEQERTLALKLQEQERLLKEGFQTESRKMQNEIQDLQKKMRQRRTCTIS

67.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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