Protein expression services for aex-2 | G-protein coupled receptor aex-2
Description
G-protein coupled receptor for the nlp-40 neuropeptide (PubMed:23583549). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:23583549). Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds (PubMed:18852466, PubMed:23583549). Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation (PubMed:18852466, PubMed:23583549). Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine (PubMed:25849533).
Family
Belongs to the G-protein coupled receptor 1 family.
Species
Caenorhabditis elegans
Length
321 amino acids
Sequence
MNSTDIIANVTKPFVENLTLGETAFYISCGIVGTVFNALVLWIALTYINTEDKPRQIIVINMTVADLLMCIVYMKTRPWLSHFNLWLCHPYYVIIWTCQMCSCLNLVWLNVDKLIYIQFPLHYYQIVNRKRLLWITAATWGGLYAMNIALVTFLKITRGSCLGVSLNPYVYLLSPIFYVVMILTSFSLSALIYCIAHNLTHMEERQRSKLFRRLFFLFSSTLWTFFTCLPYRLLYLFSIFCGETCQINNYYKTATNLFFRLLIVGIMINPVITIWTQRIYRLRLMRMFGRLRENSSTEVLMVSNRRASERPPEHTPLRCDM
Mass
37.7 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make aex-2 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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